Defending Copa Libertadores champions Internacional hammered Mexico's Jaguares 4-0 to go top of Group Six in Brazil.
A brace by Argentina midfielder Mario Bolatti helped Celso Roth's Inter claim a comfortable win as they seek to retain their title.
Bolatti put Inter ahead in the 20th minute from a corner while he doubled the lead with a header just before half-time.
In the 67th minute, a Fernando Cavenaghi shot hit the post and Leandro Damiao tapped home the rebound to make it 3-0 before Oscar rounded off the win with a shot from distance.
Jaguares' poor day was compounded when midfielder Jorge Rodriguez was sent off in injury time for hitting Oscar.