Defenders Patrice Evra and Adil Rami and midfielder Yohan Cabaye picked up knocks in the 3-0 Euro 2012 qualifying win over Albania on Friday to add to France's growing injury list.
France consolidated top spot in Group D and will qualify automatically for the finals with at least a draw in their final match at home to second-placed Bosnia on Tuesday.
"We can say we're unlucky injury wise," coach Laurent Blanc told a news conference.
France were already without the injured Karim Benzema, Frank Ribery, Eric Abidal, Bacary Sagna, Kevin Gameiro and Blaise Matuidi for Friday's game.
Evra and Rami picked up thigh injuries against Albania while midfielder Cabaye suffered an ankle injury, said Blanc, who could not yet say whether the trio would be fit to face Bosnia.