FIFA virus! Real Madrid playmaker Isco has pulled out of the Spain squad to face England with muscle fatigue. Isco is recently added another wounded after Sergio Ramos because of a shoulder injury pulled out of Spain, his club mate Nacho replace him included in the Spain squad. Who will replace Isco in Spain squad? Are Spain over their World Cup hangover at Euro 2016? Despite a solid record in qualifying of nine wins from 10 games, European champions Spain are facing several dilemmas as they prepare for the defence of their title in France next summer.